The First International Symposium on Disruptive Technologies in the Space field was held in Marseille from 4 to 6 July 2005, where it brought together around a hundred representatives of the main Space players from about ten countries in Europe, America and Japan including agencies, institutions, industries, laboratories and research organizations. It mainly dealt with subjects relating to orbital systems, through sessions devoted to the most upgradable satellite subsystems and components, such as instruments, onboard computers, detectors, propulsion systems, actuators, electronic components, etc. This symposium has help to identify and characterize present or future disruptive technologies, and their impact on the design of future satellites and launchers, as well as ground segments. It has also deal with the impact of recent technological disruptions, particularly those which have led to major changes in the definition of these various systems. Many Space companies – including GTD – have presented various papers. The poster session and the discussions between participants has help Space players to identify technologies that are undergoing major changes, those that may lead to spin-offs, and those which should benefit from further research and development activities.